Cysteine, which can be derived from the sulfur of methionine through the TSP, seems to undergo conversion into taurine via the cysteine sulfinate pathway and serves as an osmolyte, a neuromodulator, an immunomodulator, and an antioxidant (22)
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The p53/p21 pathway may not be responsible for maintaining senescence after upregulation of p53-pS15 initiates senescence in keloids
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Interestingly, in individuals with HVDAS, the ADNP-SIRT1-EB1/EB3 protein complex may regulate autophagy, which is dysregulated and negatively affects mitochondrial metabolism in autism [344]
[DOI] [PubMed] [Google Scholar] 85.Gao JH, Liu YY, Xu HX, Wu K, Zhang LL, Cheng P, Peng XH, Cao JL, Hua R, and Zhang YM